Rune
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Rune may refer to:
- Rune, a type of metal made from runite ore
- Rune equipment, tier 50 melee equipment made from rune
- Runes, stones used to cast Magic spells
- Rune essence, the raw material that players can turn into low-level runes
- Pure essence, the raw material that members can turn into higher-level runes
- Rune (The Zamorakian Undercity), a monster encountered during the fight with Zamorak, Lord of Chaos