Vine may refer to:
- Vine, an item used in Big Game Hunter
- Vine (Runespan), a floating vine in the Runespan
- Jade vine, a plant grown during Back to my Roots
- Tangle vine, a Construction item used in a Dungeon POH
- Wild jade vine, a monster fought during Back to my Roots
- Whip vine, an item that can be attached to an Abyssal whip
- Short vine, an item used during Temple Trekking
- Long vine, an item used during Temple Trekking
- Grapevine, a type of hops that yields God grapes.
- Compacted vines, an item obtained from the Anachronia Agility Course.
- Vines dropped while hunting jadinkos in the Herblore Habitat