TB or Tb may refer to:
- Trouble Brewing, an activity on the pirate island of Mos Le'Harmless
- Teleport Block, a spell that prevents a player from using teleportation for five minutes
- Tinderbox, an item used for lighting fires
- Tool belt, a belt which can hold items
- Dungeoneering tool belt, similar to the normal tool belt but for use in the Dungeoneering skill
Look for any other RuneScape related meanings of TB on the appropriate Slang dictionary page.