Sanfew serum

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For the potion flask version, see Sanfew serum flask.
Sanfew serum detail.png

Sanfew serum combines the properties of super restore and antipoison potions. Level 65 Herblore and completion of Zogre Flesh Eaters is needed to make this potion. Mixing the potion gives 160 herblore experience.

This potion can be made into a Sanfew serum flask by using at least six doses of it with a potion flask. Players do not need a specific level to turn potions into flasks.

Price per dose[edit | edit source]

Item GE price Price per dose Price per dose
(Excluding vial / flask)
Sanfew serum (1).png Sanfew serum (1) 4,021 4,021 4,019
Sanfew serum (2).png Sanfew serum (2) 3,264 1,632 1,631
Sanfew serum (3).png Sanfew serum (3) 5,021 1,674 1,673
Sanfew serum (4).png Sanfew serum (4) 6,208 1,552 1,552
Sanfew serum flask (6).png Sanfew serum flask (6) 18,845 3,141 1,522

Creation[edit | edit source]

Sanfew serum is made by adding, in order, unicorn horn dust, clean snake weed and nail beast nails to an already made 3-dose super restore potion. Partially completed Sanfew Serums are called mixture - step 1 and mixture - step 2, but are not drinkable in these forms.

Players therefore need to make sure that the unicorn horn dust is highlighted before clicking each of the vials to avoid accidentally drinking any of the Super restore. Since the intermediate potions are not drinkable, the same danger does not exist once the unicorn horn dust has been added.

Herblore experience is given for each addition of one of the secondary ingredients in this potion.

Unicorn horn dust xp Snake weed xp Nail beast nails xp Total xp
47.5 52.5 60 160
Sanfew serum (3).png Sanfew serum (3)
Herblore-Hourglass.pngMake-X GE icon.png
60 XP-2 (1.2s) / 1 (0.6s) [recipe 1]5,021
Requirements
Herblore Herblore level65
Quests Partially complete: Zogre Flesh Eaters
P2P icon.png Members only
Materials
ItemQuantityPriceTotal
Mixture - step 2 (3).pngMixture - step 2 (3)16666
Nail beast nails.pngNail beast nails1127127
Total price193
Profit4,828
  1. ^ When mixing a single potion

Production costs[edit | edit source]

Snake weed is untradeable, so its value is subjective and has not been included in the calculation.

Herb Secondaries Vial Material cost Profit Profit/XP
Clean snake weed.png: RS3 Inventory image of Clean snake weedClean snake weed Unicorn horn dust.png: RS3 Inventory image of Unicorn horn dustUnicorn horn dust
Nail beast nails.png: RS3 Inventory image of Nail beast nailsNail beast nails
Super restore.png: RS3 Inventory image of Super restoreSuper restore (3) 4,778 243 1.52
Grimy snake weed.png: RS3 Inventory image of Grimy snake weedGrimy snake weed Unicorn horn dust.png: RS3 Inventory image of Unicorn horn dustUnicorn horn dust
Nail beast nails.png: RS3 Inventory image of Nail beast nailsNail beast nails
Super restore.png: RS3 Inventory image of Super restoreSuper restore (3) 4,778 243 1.5
Clean snake weed.png: RS3 Inventory image of Clean snake weedClean snake weed Nail beast nails.png: RS3 Inventory image of Nail beast nailsNail beast nails Mixture - step 1.png: RS3 Inventory image of Mixture - step 1Mixture - step 1 (3) 4,299 722 42.92
Grimy snake weed.png: RS3 Inventory image of Grimy snake weedGrimy snake weed Nail beast nails.png: RS3 Inventory image of Nail beast nailsNail beast nails Mixture - step 1.png: RS3 Inventory image of Mixture - step 1Mixture - step 1 (3) 4,299 722 41.98
N/A Nail beast nails.png: RS3 Inventory image of Nail beast nailsNail beast nails Mixture - step 2.png: RS3 Inventory image of Mixture - step 2Mixture - step 2 (3) 193 4,828 80.47

Antipoison protection comparison[edit | edit source]

Antipoison Price/dose Seconds/dose Price/second
Antipoison.png: RS3 Inventory image of AntipoisonAntipoison (4) 202 86 2.35
Antipoison flask.png: RS3 Inventory image of Antipoison flaskAntipoison flask (6) 1,811.17 86 21.06
Super antipoison.png: RS3 Inventory image of Super antipoisonSuper antipoison (4) 2,512.25 346 5.63
Super antipoison flask.png: RS3 Inventory image of Super antipoison flaskSuper antipoison flask (6) 4,006.17 346 8.98
Antipoison+.png: RS3 Inventory image of Antipoison+Antipoison+ (4) 1,395.25 518 2.69
Antipoison+ flask.png: RS3 Inventory image of Antipoison+ flaskAntipoison+ flask (6) 5,034.67 518 9.72
Antipoison++.png: RS3 Inventory image of Antipoison++Antipoison++ (4) 785.25 720 1.09
Antipoison++ flask.png: RS3 Inventory image of Antipoison++ flaskAntipoison++ flask (6) 2,510.67 720 3.49
Sanfew serum.png: RS3 Inventory image of Sanfew serumSanfew serum (4) 1,552 86 18.05
Sanfew serum flask.png: RS3 Inventory image of Sanfew serum flaskSanfew serum flask (6) 3,140.83 86 36.52
Irit incense sticks.png: RS3 Inventory image of Irit incense sticksIrit incense sticks 16,969 600 28.28

Prayer-restoring potion comparison[edit | edit source]

  1. ^ Prayer points need to be rounded down after using the formulas.
  2. ^ If a potion is untradeable the price of the ingredients is used instead.

Extra amounts[edit | edit source]

Item Normal
amount
With holy wrench
Holy wrench.png: RS3 Inventory image of Holy wrench
With reverence
Reverence aura.png: RS3 Inventory image of Reverence aura
With holy wrench and reverence
Holy wrench.png: RS3 Inventory image of Holy wrench Reverence aura.png: RS3 Inventory image of Reverence aura
Prayer potion.png: RS3 Inventory image of Prayer potionPrayer potion 317 337

Tier 1: 327   Tier 2: 333
Tier 3: 339   Tier 4: 349

Tier 1: 347   Tier 2: 354
Tier 3: 361   Tier 4: 371

Spiritual prayer potion.png: RS3 Inventory image of Spiritual prayer potionSpiritual prayer potion
Super restore.png: RS3 Inventory image of Super restoreSuper restore 327 347

Tier 1: 337   Tier 2: 343
Tier 3: 350   Tier 4: 360

Tier 1: 357   Tier 2: 364
Tier 3: 371   Tier 4: 382

Sanfew serum.png: RS3 Inventory image of Sanfew serumSanfew serum
Replenishment potion.png: RS3 Inventory image of Replenishment potionReplenishment potion
Enhanced replenishment potion.png: RS3 Inventory image of Enhanced replenishment potionEnhanced replenishment potion
Super prayer.png: RS3 Inventory image of Super prayerSuper prayer 416 436

Tier 1: 428   Tier 2: 437
Tier 3: 445   Tier 4: 457

Tier 1: 449   Tier 2: 458
Tier 3: 467   Tier 4: 480

Prayer renewal.png: RS3 Inventory image of Prayer renewalPrayer renewal 545 575

Tier 1: 598   Tier 2: 625
Tier 3: 656   Tier 4: 704

Tier 1: 628   Tier 2: 655
Tier 3: 686   Tier 4: 734

Brightfire potion.png: RS3 Inventory image of Brightfire potionBrightfire potion
Holy overload potion.png: RS3 Inventory image of Holy overload potionHoly overload potion
Holy aggroverload.png: RS3 Inventory image of Holy aggroverloadHoly aggroverload
Extreme prayer.png: RS3 Inventory image of Extreme prayerExtreme prayer 565 584

Tier 1: 582   Tier 2: 593
Tier 3: 606   Tier 4: 621

Tier 1: 602   Tier 2: 613
Tier 3: 625   Tier 4: 643

Blessed flask.png: RS3 Inventory image of Blessed flaskBlessed flask
Super prayer renewal potion.png: RS3 Inventory image of Super prayer renewal potionSuper prayer renewal potion 912 962

Tier 1: 975   Tier 2: 1008
Tier 3: 1045   Tier 4: 1103

Tier 1: 1025   Tier 2: 1059
Tier 3: 1097   Tier 4: 1155

Overload salve.png: RS3 Inventory image of Overload salveOverload salve
Supreme overload salve.png: RS3 Inventory image of Supreme overload salveSupreme overload salve
Elder overload salve.png: RS3 Inventory image of Elder overload salveElder overload salve

Disassembly[edit | edit source]

Update history[edit | edit source]

The update history project is a work-in-progress – not all updates to this topic may be covered below. See here for how to help out!
  • patch 12 December 2016 (Update):
    • Can no longer apply a weaker anti-poison effect if a stronger effect is already active.
  • patch 14 January 2013 (Update):
    • Fixed an issue with making sanfew serums with the new Make-X interface.
  • patch 7 February 2012 (Update):
    • There is now a warning about when anti-poison is about to wear off.
    • Crafting Sanfew Serums now uses a make-x interface.
  • patch 20 January 2009 (Update):
    • The Sanfew serum from Temple Trekking has been brought in line with the recent changes to restore Summoning as well as the existing stats.