Making weapon poison++

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The methods in this guide may involve considerable risk, including (but not limited to): loss of money/items, unstable prices, and/or slow GE resale.
Reason: Unstable Prices
You can discuss this issue on the talk page or edit this page to improve it.
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Making weapon poison++
RequirementsMaking weapon poison++.png
Skills

82 Herblore

97 Farming recommended
Items
Skavid map.png: RS3 Inventory image of Skavid mapSkavid map
Ring of duelling.png: RS3 Inventory image of Ring of duellingRing of duelling
Grace of the elves.png: RS3 Inventory image of Grace of the elvesGrace of the elves recommended
Quest
Watchtower
Other
Envenomed perk from Ranch Out of Time
Results
ProfitROIExperience gained
16,913,955155.49%145,920 Herblore
Inputs (10,877,545)Outputs (27,791,500)
ItemQuantityGE Price
Poison ivy berries.pngPoison ivy berries7683,812,352
Coconut.pngCoconut7686,965,760
Cave nightshade.pngCave nightshade[1]7680
Vial.pngVial7681,536
Botanist's amulet.pngBotanist's amulet7.6897,897
ItemQuantityGE Price
Weapon poison++ (3).pngWeapon poison++ (3)81527,791,500

Weapon poison++ is made by using cave nightshade on a vial of coconut milk and poison ivy berries. Cave nightshade only spawns inside the Skavid caves and is not tradeable, so the spawn time of the nightshade is the limiting factor in how fast weapon poison++ can be made.

Cave nightshade locations.png

Cave nightshade can be found in the caves under Gu'Tanoth, east of Castle Wars. The easiest way to get there is by teleporting to the Yanille lodestone and walking to the most northern cave entrance marked on the map to the right. A skavid map is required to enter. Gloves are required for picking Nightshades.

Collectors can wait due to the fast respawn rate, which means that you can afk while doing this.

The varanusaur envenomed perk gives a 10% chance to make 4 doses instead of 3 doses when mixing Weapon Poison or Antipoison potions.

  1. ^ non-tradable