The Extreme Guthix balance is an item used in River of Blood. It is made from refined daeyalt, Ivandis's serum, and Wyrd blood that is obtained from Safalaan.
It is used to strengthen the River Salve so that it can cure the vampyrism of any human-born vampyres who cross it and diminish the insatiable hunger of true-borns. It is also used to help calm Safalaan's Wyrd bloodlust after the player subdues him.
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