Calculator:Herblore/Efficient Profit

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This calculator shows profit/losses from training the Herblore skill efficiently. This calculator assumes that you are making potions from grimy herbs, using a Portable well, have the Scroll of cleansing, and are decanting into Potion flasks. These numbers are estimates based on the likelihood of the effects of the portable well and the scroll of cleansing, but they are quite reliable. Untradeable potions and potions requiring untradeable ingredients are omitted as this guide/calculator is designed for bulk training with concern for profit.


Reasoning:[edit source]

Grimy herbs: Grimy herbs are frequently cheaper than their clean alternatives and the experience from cleaning them is not negligible, as opposed to making unfinished potions. If profit/expenditure is your main concern, cleaning your own herbs and making your own unfinished potions is worth the time.

Portable well: The portable well boosts Herblore experience by 10% and gives a 5% chance of making an extra potion. This 5% is applied when making unfinished potions and again when finishing potions with secondary ingredients. Portable wells are frequently hosted at the Combat academy, which you can use at no cost to you, though it is nice to help out the community by deploying some portable wells that you have purchased.

Scroll of cleansing: The scroll of cleansing can be purchased from Marmaros Thokson in Daemonheim for 20,000 Dungeoneering tokens. The scroll gives a 12.5% chance that a potion will be created twice as fast as usual. The scroll also gives a 10% chance of salvaging a herb added to a vial of water and salvaging a secondary ingredient when added to an unfinished potion.

Decanting to Potion flasks: Decanting to flasks does not always increase profit. To see if decanting is profitable, check the Calculator:Herblore/Flask decanting page. However, decanting to flasks can be done for free, in bulk (noted items), and almost instantly with the help of Teplin Macagan after completion of As a First Resort. Because this can be done so quickly, can be immensely profitable, and if profit is your motive, I highly suggest only making potions which are profitable to decant. Note that the Grand exchange limits players to buying 1K potion flasks per 4 hours. This means that a maximum of 6K flasks can be purchased during 1 day under optimal circumstances.

Process (standard potions):[edit source]

The following is the process to replicate (as close as possible) the optimal calculations shown in the below table. Buying 1,000 herbs was used as a way to calculate more accurate averages for the sake of representation. With smaller sample sizes, results will vary more widely, but over time will average out to the calculations shown in the below table.

1. Buy 1,000 grimy variants of the herb for your selected potion. Herbs can be slower to purchase at GE market prices, but the more profitable potions can still turn a significant profit even while buying herbs at higher-than-market price.

2. Clean your grimy herbs. This is done fastest by setting a Bank preset for quick withdrawing.

3. Find a world where a Portable well is being hosted. This information can be found by searching for 'portable locations' in the RuneScape forums.

4. Add your herbs to vials of water using the portable well. By adding 1,000 herbs to vials of water, you will yield (on average) 1050 unfinished potions due to the effect of the portable well. Due to the effect of the scroll of cleansing, you will have saved (on average) 100 herbs. By adding those 100 herbs to vials of water, you will yield (on average) 105 unfinished potions and saved (on average) 10 herbs. By adding those 10 herbs to vials of water, you will yield (on average) 10 unfinished potions and saved (on average) 1 herb. This herb (on average) will make 1 unfinished potion and will not be saved. This process will yield in total, and of course on average, 1,166 unfinished potions and use 1,111 vials of water.

5. Due to the 10% chance to save secondary ingredients, your 1,166 unfinished potions will require (on average) 1,060 secondary ingredients. (1,060 * 1.1 = 1,166) Buy a little more than this amount (to avoid having to go back to the Grand exchange) and add them to your unfinished potions at the portable well. The 5% chance to make an extra potion will be applied again over this process at the portable well. This will yield (on average) 1,224 finished 3-dose potions.

6. Buy 612 (half the amount of your 3-dose potions rounded down) Potion flasks at the Grand exchange. Bring your noted potion flasks and noted 3-dose potions to Teplin Macagan and have him decant your potions into your flasks. Sell these flasks at the grand exchange. It may take some time for your flasks to sell at market prices, but again the more profitable potions may still turn a significant profit even selling at a little lower than market price.


Potion Level
Req.
XP Cost of Initial Ingredients Cost of 1060
Secondary Ingredients
Cost of 612
Potion Flasks
Total Cost Price of 612
Full Flasks
Profit/Loss Per
Herb Purchased
Attack potion (3).png Attack potion 1 25 Grimy guam.png 1000 X Grimy guam 337,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 414,770
Eye of newt.png 1060 X Eye of newt
8,480
Potion flask.png 612 X Potion flask
3,560,004
3,983,254 Attack flask (6).png 612 X Attack flask (6)
3,747,276
-235.98
Ranging potion (3).png Ranging potion 3 30 Grimy guam.png 1000 X Grimy guam 337,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 414,770
Redberries.png 1060 X Redberries
841,640
Potion flask.png 612 X Potion flask
3,560,004
4,816,414 Ranging flask (6).png 612 X Ranging flask (6)
8,266,284
3,449.87
Magic potion (3).png Magic potion 5 35 Grimy tarromin.png 1000 X Grimy tarromin 46,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 123,770
Yellow bead.png 1060 X Yellow bead
745,180
Potion flask.png 612 X Potion flask
3,560,004
4,428,954 Magic flask (6).png 612 X Magic flask (6)
8,708,148
4,279.19
Strength potion (3).png Strength potion 7 4 Grimy tarromin.png 1000 X Grimy tarromin 46,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 123,770
Limpwurt root.png 1060 X Limpwurt root
1,799,880
Potion flask.png 612 X Potion flask
3,560,004
5,483,654 Strength flask (6).png 612 X Strength flask (6)
4,369,680
-1,113.97
Defence potion (3).png Defence potion 9 45 Grimy marrentill.png 1000 X Grimy marrentill 1,312,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 1,389,770
Bear fur.png 1060 X Bear fur
491,840
Potion flask.png 612 X Potion flask
3,560,004
5,441,614 Defence flask (6).png 612 X Defence flask (6)
5,584,500
142.89
Antipoison (3).png Antipoison 13 50 Grimy marrentill.png 1000 X Grimy marrentill 1,312,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 1,389,770
Unicorn horn dust.png 1060 X Unicorn horn dust
927,500
Potion flask.png 612 X Potion flask
3,560,004
5,877,274 Antipoison flask (6).png 612 X Antipoison flask (6)
5,856,840
-20.43
Guthix rest (3).png Guthix rest 18 59.5 Grimy harralander.png 1000 X Grimy harralander 107,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 184,770
Clean marrentill.png 1060 X Clean marrentill
1,427,820
Potion flask.png 612 X Potion flask
3,560,004
5,172,594 Guthix rest flask (6).png 612 X Guthix rest flask (6)
8,907,048
3,734.45
Restore potion (3).png Restore potion 22 62.5 Grimy harralander.png 1000 X Grimy harralander 107,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 184,770
Red spiders' eggs.png 1060 X Red spiders' eggs
1,718,260
Potion flask.png 612 X Potion flask
3,560,004
5,463,034 Restore flask (6).png 612 X Restore flask (6)
6,464,556
1,001.52
Energy potion (3).png Energy potion 26 67.5 Grimy harralander.png 1000 X Grimy harralander 107,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 184,770
Chocolate dust.png 1060 X Chocolate dust
506,680
Potion flask.png 612 X Potion flask
3,560,004
4,251,454 Energy flask (6).png 612 X Energy flask (6)
5,875,812
1,624.36
Agility potion (3).png Agility potion 34 80 Grimy toadflax.png 1000 X Grimy toadflax 6,216,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 6,293,770
Toad's legs.png 1060 X Toad's legs
583,000
Potion flask.png 612 X Potion flask
3,560,004
10,436,774 Agility flask (6).png 612 X Agility flask (6)
5,717,304
-4,719.47
Combat potion (3).png Combat potion 36 84 Grimy harralander.png 1000 X Grimy harralander 107,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 184,770
Goat horn dust.png 1060 X Goat horn dust
1,359,980
Potion flask.png 612 X Potion flask
3,560,004
5,104,754 Combat flask (6).png 612 X Combat flask (6)
5,916,204
811.45
Prayer potion (3).png Prayer potion 38 87.5 Grimy ranarr.png 1000 X Grimy ranarr 1,510,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 1,587,770
Snape grass.png 1060 X Snape grass
80,560
Potion flask.png 612 X Potion flask
3,560,004
5,228,334 Prayer flask (6).png 612 X Prayer flask (6)
6,539,832
1,311.5
Summoning potion (3).png Summoning potion 40 92 Grimy spirit weed.png 1000 X Grimy spirit weed 7,205,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 7,282,770
Cockatrice egg.png 1060 X Cockatrice egg
4,594,040
Potion flask.png 612 X Potion flask
3,560,004
15,436,814 Summoning flask (6).png 612 X Summoning flask (6)
18,352,044
2,915.23
Divination potion (3).png Divination potion 43 97.5 Grimy spirit weed.png 1000 X Grimy spirit weed 7,205,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 7,282,770
Rabbit foot.png 1060 X Rabbit foot
2,154,980
Potion flask.png 612 X Potion flask
3,560,004
12,997,754 Divination flask (6).png 612 X Divination flask (6)
2,200,140
-10,797.61
Super attack (3).png Super attack 45 100 Grimy irit.png 1000 X Grimy irit 3,972,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 4,049,770
Eye of newt.png 1060 X Eye of newt
8,480
Potion flask.png 612 X Potion flask
3,560,004
7,618,254 Super attack flask (6).png 612 X Super attack flask (6)
6,771,780
-846.47
Super antipoison (3).png Super antipoison 48 106.3 Grimy irit.png 1000 X Grimy irit 3,972,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 4,049,770
Unicorn horn dust.png 1060 X Unicorn horn dust
927,500
Potion flask.png 612 X Potion flask
3,560,004
8,537,274 Super antipoison flask (6).png 612 X Super antipoison flask (6)
10,479,888
1,942.61
Fishing potion (3).png Fishing potion 50 112.5 Grimy avantoe.png 1000 X Grimy avantoe 748,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 825,770
Snape grass.png 1060 X Snape grass
80,560
Potion flask.png 612 X Potion flask
3,560,004
4,466,334 Fishing flask (6).png 612 X Fishing flask (6)
4,439,448
-26.89
Super energy (3).png Super energy 52 117.5 Grimy avantoe.png 1000 X Grimy avantoe 748,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 825,770
Mort myre fungus.png 1060 X Mort myre fungus
2,661,660
Potion flask.png 612 X Potion flask
3,560,004
7,047,434 Super energy flask (6).png 612 X Super energy flask (6)
7,760,160
712.73
Hunter potion (3).png Hunter potion 53 120 Grimy avantoe.png 1000 X Grimy avantoe 748,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 825,770
Kebbit teeth dust.png 1060 X Kebbit teeth dust
3,975,000
Potion flask.png 612 X Potion flask
3,560,004
8,360,774 Hunter flask (6).png 612 X Hunter flask (6)
3,651,804
-4,708.97
Runecrafting potion (3).png Runecrafting potion 54 122.5 Grimy wergali.png 1000 X Grimy wergali 2,218,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 2,295,770
Fallfaced wool.png 1060 X Fallfaced wool
58,300
Potion flask.png 612 X Potion flask
3,560,004
5,914,074 Runecrafting flask (6).png 612 X Runecrafting flask (6)
1,919,844
-3,994.23
Super strength (3).png Super strength 55 125 Grimy kwuarm.png 1000 X Grimy kwuarm 7,067,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 7,144,770
Limpwurt root.png 1060 X Limpwurt root
1,799,880
Potion flask.png 612 X Potion flask
3,560,004
12,504,654 Super strength flask (6).png 612 X Super strength flask (6)
9,555,768
-2,948.89
Fletching potion (3).png Fletching potion 58 132 Grimy wergali.png 1000 X Grimy wergali 2,218,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 2,295,770
Wimpy feather.png 1060 X Wimpy feather
365,700
Potion flask.png 612 X Potion flask
3,560,004
6,221,474 Fletching flask (6).png 612 X Fletching flask (6)
3,597,948
-2,623.53
Weapon poison (3).png Weapon poison 60 137.5 Grimy kwuarm.png 1000 X Grimy kwuarm 7,067,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 7,144,770
Dragon scale dust.png 1060 X Dragon scale dust
183,380
Potion flask.png 612 X Potion flask
3,560,004
10,888,154 Weapon poison flask (6).png 612 X Weapon poison flask (6)
3,271,140
-7,617.01
Super restore (3).png Super restore 63 142.5 Grimy snapdragon.png 1000 X Grimy snapdragon 1,541,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 1,618,770
Red spiders' eggs.png 1060 X Red spiders' eggs
1,718,260
Potion flask.png 612 X Potion flask
3,560,004
6,897,034 Super restore flask (6).png 612 X Super restore flask (6)
7,475,580
578.55
Super defence (3).png Super defence 66 150 Grimy cadantine.png 1000 X Grimy cadantine 2,189,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 2,266,770
White berries.png 1060 X White berries
4,443,520
Potion flask.png 612 X Potion flask
3,560,004
10,270,294 Super defence flask (6).png 612 X Super defence flask (6)
8,961,516
-1,308.78
Antipoison+ (3).png Antipoison+ 68 155 Grimy toadflax.png 1000 X Grimy toadflax 6,216,000
Coconut milk.png 1111 X Coconut milk 4,194,025
Total cost: 10,410,025
Yew roots.png 1060 X Yew roots
991,100
Potion flask.png 612 X Potion flask
3,560,004
14,961,129 Antipoison+ flask (6).png 612 X Antipoison+ flask (6)
14,542,344
-418.78
Antifire (3).png Antifire 69 157.5 Grimy lantadyme.png 1000 X Grimy lantadyme 5,823,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 5,900,770
Dragon scale dust.png 1060 X Dragon scale dust
183,380
Potion flask.png 612 X Potion flask
3,560,004
9,644,154 Antifire flask (6).png 612 X Antifire flask (6)
10,506,816
862.66
Super ranging potion (3).png Super ranging potion 72 162.5 Grimy dwarf weed.png 1000 X Grimy dwarf weed 4,696,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 4,773,770
Wine of Zamorak.png 1060 X Wine of Zamorak
6,330,320
Potion flask.png 612 X Potion flask
3,560,004
14,664,094 Super ranging flask (6).png 612 X Super ranging flask (6)
12,754,080
-1,910.01
Super magic potion (3).png Super magic potion 76 172.5 Grimy lantadyme.png 1000 X Grimy lantadyme 5,823,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 5,900,770
Potato cactus.png 1060 X Potato cactus
1,586,820
Potion flask.png 612 X Potion flask
3,560,004
11,047,594 Super magic flask (6).png 612 X Super magic flask (6)
9,928,476
-1,119.12
Invention potion (3).png Invention potion 77 175 Grimy snapdragon.png 1000 X Grimy snapdragon 1,541,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 1,618,770
Chinchompa residue.png 1060 X Chinchompa residue
55,120
Potion flask.png 612 X Potion flask
3,560,004
5,233,894 Invention flask (6).png 612 X Invention flask (6)
2,191,572
-3,042.32
Zamorak brew (3).png Zamorak brew 78 175 Grimy torstol.png 1000 X Grimy torstol 5,388,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 5,465,770
Jangerberries.png 1060 X Jangerberries
560,740
Potion flask.png 612 X Potion flask
3,560,004
9,586,514 Zamorak brew flask (6).png 612 X Zamorak brew flask (6)
4,987,188
-4,599.33
Antipoison++ (3).png Antipoison++ 79 177.5 Grimy irit.png 1000 X Grimy irit 3,972,000
Coconut milk.png 1111 X Coconut milk 4,194,025
Total cost: 8,166,025
Magic roots.png 1060 X Magic roots
3,459,840
Potion flask.png 612 X Potion flask
3,560,004
15,185,869 Antipoison++ flask (6).png 612 X Antipoison++ flask (6)
8,717,940
-6,467.93
Saradomin brew (3).png Saradomin brew 81 180 Grimy toadflax.png 1000 X Grimy toadflax 6,216,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 6,293,770
Crushed nest.png 1060 X Crushed nest
1,220,060
Potion flask.png 612 X Potion flask
3,560,004
11,073,834 Saradomin brew flask (6).png 612 X Saradomin brew flask (6)
12,328,740
1,254.91
Aggression potion (3).png Aggression potion 82 185 Grimy bloodweed.png 1000 X Grimy bloodweed 19,514,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 19,591,770
Searing ashes.png 1060 X Searing ashes
43,438,800
Potion flask.png 612 X Potion flask
3,560,004
66,590,574 Aggression flask (6).png 612 X Aggression flask (6)
64,502,964
-2,087.61
Prayer renewal (3).png Prayer renewal 94 190 Grimy fellstalk.png 1000 X Grimy fellstalk 4,385,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 4,462,770
Morchella mushroom.png 1060 X Morchella mushroom
2,988,140
Potion flask.png 612 X Potion flask
3,560,004
11,010,914 Prayer renewal flask (6).png 612 X Prayer renewal flask (6)
10,643,904
-367.01

Process (potions made from other potions):[edit source]

Some potions such as Super Guthix rest and Super Zamorak brew are made by adding additional ingredients to a complete potion. This changes the calculations slightly, so this type of potion is in a separate table. This guide/table assumes that you are making the initial potion from scratch.

1. Make the initial potions just as described in the first process, but do not decant the potions into flasks. This will leave you with (on average) 1,224 complete potions.

2. Due to the 10% chance to save secondary ingredients, your 1,224 potions will require (on average) 1,114 tertiary ingredients. (1,113.72 * 1.1 ≈ 1,224) Buy a little more than this amount (to avoid having to go back to the Grand exchange) and add them to your potions at the portable well. The 5% chance to make an extra potion will be applied again over this process at the portable well. This will yield (on average) 1,285 finished 3-dose potions.

3. Buy 642 (half the amount of your 3-dose potions rounded down) Potion flasks at the Grand exchange. Bring your noted potion flasks and noted 3-dose potions to Teplin Macagan and have him decant your potions into your flasks. Sell these flasks at the grand exchange. It may take some time for your flasks to sell at market prices, but again the more profitable potions may still turn a significant profit even selling at a little lower than market price.

Potion Level
Req.
XP Cost of Initial Ingredients Cost of 1060
Secondary Ingredients
Cost of 1114
Tertiary Ingredients
Cost of 642
Potion Flasks
Total Cost Price of 642
Full Flasks
Profit/Loss Per
Herb Purchased
Guthix balance (3).png Guthix balance 22 50 Grimy harralander.png 1000 X Grimy harralander 107,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 184,770
Red spiders' eggs.png 1060 X Red spiders' eggs
1,718,260
Garlic.png 1114 X Garlic 543,632
Silver dust.png 1114 X Silver dust 1,218,716
Total cost: 1,762,348
Potion flask.png 642 X Potion flask
3,734,514
7,399,892 Guthix balance flask (6).png 642 X Guthix balance flask (6)
4,193,544
-3,206.35
Super hunter (3).png Super hunter 64 145 Grimy avantoe.png 1000 X Grimy avantoe 748,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 825,770
Kebbit teeth dust.png 1060 X Kebbit teeth dust
3,975,000
Rabbit teeth.png 1114 X Rabbit teeth 145,934 Potion flask.png 642 X Potion flask
3,734,514
8,681,218 Super hunter flask (6).png 642 X Super hunter flask (6)
2,772,156
-5,909.06
Super divination (3).png Super divination 70 160 Grimy spirit weed.png 1000 X Grimy spirit weed 7,205,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 7,282,770
Rabbit foot.png 1060 X Rabbit foot
2,154,980
Zygomite fruit.png 1114 X Zygomite fruit 74,638 Potion flask.png 642 X Potion flask
3,734,514
13,246,902 Super divination flask (6).png 642 X Super divination flask (6)
3,272,274
-9,974.63
Super runecrafting (3).png Super runecrafting 75 170 Grimy wergali.png 1000 X Grimy wergali 2,218,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 2,295,770
Fallfaced wool.png 1060 X Fallfaced wool
58,300
Yak milk.png 1114 X Yak milk 5,027,482 Potion flask.png 642 X Potion flask
3,734,514
11,116,066 Super runecrafting flask (6).png 642 X Super runecrafting flask (6)
2,419,698
-8,696.37
Super invention (3).png Super invention 87 220 Grimy snapdragon.png 1000 X Grimy snapdragon 1,541,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 1,618,770
Chinchompa residue.png 1060 X Chinchompa residue
55,120
Spider fangs.png 1114 X Spider fangs 2,105,460 Potion flask.png 642 X Potion flask
3,734,514
7,513,864 Super invention flask (6).png 642 X Super invention flask (6)
3,889,878
-3,623.99


Super Saradomin brew (3).png Super Saradomin brew 93 180 Grimy toadflax.png 1000 X Grimy toadflax 6,216,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 6,293,770
Crushed nest.png 1060 X Crushed nest
1,220,060
Wine of Saradomin.png 1114 X Wine of Saradomin 62,083,220 Potion flask.png 642 X Potion flask
3,734,514
73,331,564 Super Saradomin brew flask (6).png 642 X Super Saradomin brew flask (6)
77,466,930
4,135.37
Super Zamorak brew (3).png Super Zamorak brew 93 180 Grimy torstol.png 1000 X Grimy torstol 5,388,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 5,465,770
Jangerberries.png 1060 X Jangerberries
560,740
Wine of Zamorak.png 1114 X Wine of Zamorak 6,652,808 Potion flask.png 642 X Potion flask
3,734,514
16,413,832 Super Zamorak brew flask (6).png 642 X Super Zamorak brew flask (6)
12,392,526
-4,021.31
Super Guthix rest (3).png Super Guthix rest 93 59.5 Grimy harralander.png 1000 X Grimy harralander 107,000
Vial of water.png 1111 X Vial of water 77,770
Total cost: 184,770
Clean marrentill.png 1060 X Clean marrentill
1,427,820
Wine of Guthix.png 1114 X Wine of Guthix 1,262,162 Potion flask.png 642 X Potion flask
3,734,514
6,609,266 Super Guthix brew flask (6).png 642 X Super Guthix brew flask (6)
10,762,488
4,153.22

Conclusion:[edit source]

Making the flasks in the bottom table is generally not worth it if your interest is profit. The only exception is the Super Guthix rest, which can be solid money and decent experience. If your goal is to maximize experience without losing any money, it's generally best to sort the top table by XP in descending order and pick the first potion that you can make that yields a profit. It may be that there is a higher experience, profitable potion for you if you don't decant to flasks so be sure to check out other methods!