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For the potion flask version, see Antipoison++ flask.
Antipoison++ detail.png

Antipoison++ are made by mixing clean irit and magic roots in a vial of coconut milk, requiring 79 Herblore and giving 177.5 Herblore experience.

Antipoison++ cures poison and provide the longest possible immunity to poison, which is 12 minutes. This makes them far more useful than other types of antipoison potions, eliminating the need to drink constantly.

If your antipoison is about to run out you'll get the message: "Your immunity to poison is about to expire."

Price per Dose[edit | edit source]

Item GE price Price per dose
Antipoison++ (1).png Antipoison++ (1) 1,061 1,061
Antipoison++ (2).png Antipoison++ (2) 2,257 1,129
Antipoison++ (3).png Antipoison++ (3) 2,913 971
Antipoison++ (4).png Antipoison++ (4) 2,869 717
Antipoison++ flask (6).png Antipoison++ flask (6) 11,854 1,976

Creation[edit | edit source]

Antipoison++ (4).png Antipoison++ (4)
Herblore-Hourglass.pngMake-X GE icon.png
177.5 XP-2 (1.2s) / 1 (0.6s) [recipe 1]2,869
Herblore Herblore level79
P2P icon.png Members only
Antipoison++ (unf).pngAntipoison++ (unf)1N/A-
Magic roots.pngMagic roots13,9183,918
  1. ^ When mixing a single potion

Flask[edit | edit source]

This potion can be made into an antipoison++ flask by using at least six doses of it with a potion flask. Players do not need a specific level to turn potions into flasks.

Production costs[edit | edit source]

HerbSecondaryVialMaterial costProfitProfit/XP
Clean irit.png Clean iritMagic roots.png Magic rootsCoconut milk.png Coconut milk12,514-9,601-53.79
Grimy irit.png Grimy iritMagic roots.png Magic rootsCoconut milk.png Coconut milk12,453-9,540-50.93
N/AMagic roots.png Magic rootsIrit potion (unf).png Irit potion (unf)9,383-6,470-36.45
Grimy irit.pngClean irit.png + Coconut milk.png = Antipoison++ (unf).png

Grimy irit is cleaned to become clean irit added to a vial of coconut milk to make antipoison++ (unf)

Antipoison++ (unf).png + Magic roots.png = Antipoison++ (3).png
Then add magic roots to make a 4-dose Antipoison++.

Antipoison protection comparison[edit | edit source]

  • Prices based on price for (3) dose potions. Expect some variation when buying potions decanted to other dose counts.
Antipoison Price/dose Seconds/dose Price/second
Antipoison (4).png Antipoison 89 86 1.03
Super antipoison (4).png Super antipoison 1,999 346 5.78
Antipoison+ (4).png Antipoison+ 1,052 518 2.03
Antipoison++ (4).png Antipoison++ 971 720 1.35
Sanfew serum (4).png Sanfew serum 1,714.67 86 19.94
Irit incense sticks.png Irit incense sticks 5,312 600 8.85

Drop sources[edit | edit source]

Antipoison++ (4)[edit | edit source]

This list was created dynamically. For help, see the FAQ.
To force an update of this list, click here.
For an exhaustive list of all known sources for this item, see here (include RDT).
Corporeal Beast785 Multicombat.png40 (noted)UncommonP2P icon.png

Disassembly[edit | edit source]

Update history[edit | edit source]

The update history project is a work-in-progress – not all updates to this topic may be covered below. See here for how to help out!
  • patch 12 December 2016 (Update):
    • Can no longer apply a weaker anti-poison effect if a stronger effect is already active.
  • patch 7 February 2012 (Update):
    • There is now a warning about when anti-poison is about to wear off.