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For the potion flask version, see Antipoison++ flask.
Antipoison++ detail.png

Antipoison++ are made by mixing clean irit and magic roots in a vial of coconut milk, requiring 79 Herblore and giving 177.5 Herblore experience.

Antipoison++ cures poison and provide the longest possible immunity to poison(aside from Ogre flask (thermal) which can last up to 14 minutes), which is 12 minutes. This makes them far more useful than other types of antipoison potions, eliminating the need to drink constantly.

If your antipoison is about to run out you'll get the message: "Your immunity to poison is about to expire."

Price per Dose[edit | edit source]

Item GE price Price per dose Price per dose (Excluding vial / flask)
Antipoison++ (1).png Antipoison++ (1) 993 993 991
Antipoison++ (2).png Antipoison++ (2) 2,186 1,093 1,092
Antipoison++ (3).png Antipoison++ (3) 3,937 1,312 1,312
Antipoison++ (4).png Antipoison++ (4) 3,786 947 946
Antipoison++ flask (6).png Antipoison++ flask (6) 18,340 3,057 1,769

Creation[edit | edit source]

Antipoison++ (4).png Antipoison++ (4)
Herblore-Hourglass.pngMake-X GE icon.png
177.5 XP-2 (1.2s) / 1 (0.6s) [recipe 1]3,786
Herblore Herblore level79
P2P icon.png Members only
Antipoison++ (unf).pngAntipoison++ (unf)1N/A-
Magic roots.pngMagic roots13,7883,788
  1. ^ When mixing a single potion

Flask[edit | edit source]

This potion can be made into an antipoison++ flask by using at least six doses of it with a potion flask. Players do not need a specific level to turn potions into flasks.

Production costs[edit | edit source]

HerbSecondaryVialMaterial costProfitProfit/XP
Clean irit.png Clean iritMagic roots.png Magic rootsCoconut milk.png Coconut milk17,832-13,895-77.84
Grimy irit.png Grimy iritMagic roots.png Magic rootsCoconut milk.png Coconut milk17,504-13,567-72.43
N/AMagic roots.png Magic rootsIrit potion (unf).png Irit potion (unf)9,994-6,057-34.12
Grimy irit.pngClean irit.png + Coconut milk.png = Antipoison++ (unf).png

Grimy irit is cleaned to become clean irit added to a vial of coconut milk to make antipoison++ (unf)

Antipoison++ (unf).png + Magic roots.png = Antipoison++ (3).png
Then add magic roots to make a 4-dose Antipoison++.

Antipoison protection comparison[edit | edit source]

  • Prices based on price for (3) dose potions. Expect some variation when buying potions decanted to other dose counts.
Antipoison Price/dose Seconds/dose Price/second
Antipoison (4).png Antipoison 118.33 86 1.38
Super antipoison (4).png Super antipoison 2,835 346 8.19
Antipoison+ (4).png Antipoison+ 1,132.33 518 2.19
Antipoison++ (4).png Antipoison++ 1,312.33 720 1.82
Sanfew serum (4).png Sanfew serum 1,714.67 86 19.94
Irit incense sticks.png Irit incense sticks 8,459 600 14.1

Drop sources[edit | edit source]

Antipoison++ (4)[edit | edit source]

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For an exhaustive list of all known sources for this item, see here (include RDT).

Disassembly[edit | edit source]

Update history[edit | edit source]

The update history project is a work-in-progress – not all updates to this topic may be covered below. See here for how to help out!
  • patch 12 December 2016 (Update):
    • Can no longer apply a weaker anti-poison effect if a stronger effect is already active.
  • patch 7 February 2012 (Update):
    • There is now a warning about when anti-poison is about to wear off.